L62P (p.Leu62Pro) variant of TPO (Thyroid peroxidase)
L62P (p.Leu62Pro) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and published literature.
L62P (p.Leu62Pro) variant details
- p.Leu62Pro
- gnomAD 3-184375558-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.656
- CADD 27.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available