D51D (p.Asp51Asp) variant of TPO (Thyroid peroxidase)
D51D (p.Asp51Asp) in TPO (Thyroid peroxidase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
D51D (p.Asp51Asp) variant details
- p.Asp51Asp
- gnomAD 3-184375545-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.292
- CADD 9.77
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available