A71V (p.Ala71Val) variant of TPO (Thyroid peroxidase)
A71V (p.Ala71Val) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
A71V (p.Ala71Val) variant details
- p.Ala71Val
- gnomAD 3-184375552-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- CADD 22.50
- PolyPhen-2 0.01
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available