A71T (p.Ala71Thr) variant of TPO (Thyroid peroxidase)
A71T (p.Ala71Thr) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
A71T (p.Ala71Thr) variant details
- p.Ala71Thr
- rs1714316088
- gnomAD 3-184375553-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- CADD 14.60
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available