T141T (p.Thr141Thr) variant of TPMT (Thiopurine S-methyltransferase)
T141T (p.Thr141Thr) in TPMT (Thiopurine S-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data, published literature, and structural context.
T141T (p.Thr141Thr) variant details
- p.Thr141Thr
- gnomAD 6-18139034-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.0851
- CADD 5.33
- SIFT 0.04
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available