S85T (p.Ser85Thr) variant of TPMT (Thiopurine S-methyltransferase)
S85T (p.Ser85Thr) in TPMT (Thiopurine S-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
S85T (p.Ser85Thr) variant details
- p.Ser85Thr
- TOPMed rs1457901774
- gnomAD rs1457901774
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.05
- CADD 8.19
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available