S85N (p.Ser85Asn) variant of TPMT (Thiopurine S-methyltransferase)
S85N (p.Ser85Asn) in TPMT (Thiopurine S-methyltransferase) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The record also includes variant effect predictions and structural context.
S85N (p.Ser85Asn) variant details
- p.Ser85Asn
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- MetaLR 0.11
- MetaSVM -1.02
- SIFT 0.14
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available