G3D (p.Gly3Asp) variant of TPMT (Thiopurine S-methyltransferase)
G3D (p.Gly3Asp) in TPMT (Thiopurine S-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
G3D (p.Gly3Asp) variant details
- p.Gly3Asp
- ESP rs143125661
- ExAC rs143125661
- TOPMed rs143125661
- gnomAD rs143125661
- Missense
- Variant Prioritization Score for Impact Estimate 0.106
- REVEL 0.13
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available