G36D (p.Gly36Asp) variant of TPMT (Thiopurine S-methyltransferase)
G36D (p.Gly36Asp) in TPMT (Thiopurine S-methyltransferase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
G36D (p.Gly36Asp) variant details
- p.Gly36Asp
- TOPMed rs1207054487
- gnomAD rs1207054487
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.17
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 0.83
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available