G144G (p.Gly144Gly) variant of TPMT (Thiopurine S-methyltransferase)
G144G (p.Gly144Gly) in TPMT (Thiopurine S-methyltransferase) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
G144G (p.Gly144Gly) variant details
- p.Gly144Gly
- gnomAD 6-18139025-G-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.232
- CADD 9.26
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available