W194* (p.Trp194Ter) variant of TOP2A (DNA topoisomerase 2-alpha)
W194* (p.Trp194Ter) in TOP2A (DNA topoisomerase 2-alpha) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.86 / 1. The record also includes population frequency data and structural context.
W194* (p.Trp194Ter) variant details
- p.Trp194Ter
- Ensembl rs2035341946
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.855
- CADD 36.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available