V63I (p.Val63Ile) variant of TOP2A (DNA topoisomerase 2-alpha)
V63I (p.Val63Ile) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
V63I (p.Val63Ile) variant details
- p.Val63Ile
- Ensembl rs2143696259
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.13
- CADD 22.50
- PolyPhen-2 0.08
- SIFT 0.10
- Population evidence available
- Structural context available