V137I (p.Val137Ile) variant of TOP2A (DNA topoisomerase 2-alpha)
V137I (p.Val137Ile) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
V137I (p.Val137Ile) variant details
- p.Val137Ile
- Ensembl rs2143687902
- Missense
- Variant Prioritization Score for Impact Estimate 0.354
- REVEL 0.08
- CADD 22.90
- PolyPhen-2 0.19
- SIFT 0.02
- Population evidence available
- Structural context available