S183N (p.Ser183Asn) variant of TOP2A (DNA topoisomerase 2-alpha)
S183N (p.Ser183Asn) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S183N (p.Ser183Asn) variant details
- p.Ser183Asn
- Ensembl rs2143686743
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.10
- CADD 20.50
- PolyPhen-2 0.04
- SIFT 0.21
- Population evidence available
- Structural context available