S174N (p.Ser174Asn) variant of TOP2A (DNA topoisomerase 2-alpha)
S174N (p.Ser174Asn) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
S174N (p.Ser174Asn) variant details
- p.Ser174Asn
- Ensembl rs2143686893
- Missense
- Variant Prioritization Score for Impact Estimate 0.691
- REVEL 0.62
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available