Q7P (p.Gln7Pro) variant of TOP2A (DNA topoisomerase 2-alpha)
Q7P (p.Gln7Pro) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
Q7P (p.Gln7Pro) variant details
- p.Gln7Pro
- TOPMed rs1440570848
- gnomAD rs1440570848
- Missense
- Variant Prioritization Score for Impact Estimate 0.333
- REVEL 0.12
- CADD 25.60
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available