Q7H (p.Gln7His) variant of TOP2A (DNA topoisomerase 2-alpha)
Q7H (p.Gln7His) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
Q7H (p.Gln7His) variant details
- p.Gln7His
- TOPMed rs1298821177
- gnomAD rs1298821177
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.05
- CADD 31.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available