Q192H (p.Gln192His) variant of TOP2A (DNA topoisomerase 2-alpha)
Q192H (p.Gln192His) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data and structural context.
Q192H (p.Gln192His) variant details
- p.Gln192His
- Ensembl rs1200411904
- Missense
- Variant Prioritization Score for Impact Estimate 0.664
- REVEL 0.52
- CADD 35.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available