N171K (p.Asn171Lys) variant of TOP2A (DNA topoisomerase 2-alpha)
N171K (p.Asn171Lys) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
N171K (p.Asn171Lys) variant details
- p.Asn171Lys
- Ensembl rs867525891
- Missense
- Variant Prioritization Score for Impact Estimate 0.476
- REVEL 0.65
- CADD 22.60
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available