K96Q (p.Lys96Gln) variant of TOP2A (DNA topoisomerase 2-alpha)
K96Q (p.Lys96Gln) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
K96Q (p.Lys96Gln) variant details
- p.Lys96Gln
- ExAC rs773676790
- TOPMed rs773676790
- gnomAD rs773676790
- Missense
- Variant Prioritization Score for Impact Estimate 0.621
- REVEL 0.58
- CADD 29.70
- PolyPhen-2 0.94
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available