G69D (p.Gly69Asp) variant of TOP2A (DNA topoisomerase 2-alpha)
G69D (p.Gly69Asp) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
G69D (p.Gly69Asp) variant details
- p.Gly69Asp
- Ensembl rs2143696194
- Missense
- Variant Prioritization Score for Impact Estimate 0.509
- REVEL 0.32
- CADD 23.90
- PolyPhen-2 0.72
- SIFT 0.30
- Population evidence available
- Structural context available