D86N (p.Asp86Asn) variant of TOP2A (DNA topoisomerase 2-alpha)
D86N (p.Asp86Asn) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
D86N (p.Asp86Asn) variant details
- p.Asp86Asn
- Ensembl rs2143695982
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.48
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available