A93V (p.Ala93Val) variant of TOP2A (DNA topoisomerase 2-alpha)
A93V (p.Ala93Val) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
A93V (p.Ala93Val) variant details
- p.Ala93Val
- Ensembl rs2035386452
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.44
- CADD 31.00
- PolyPhen-2 0.59
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.5e-05)
- Structural context available