A182V (p.Ala182Val) variant of TOP2A (DNA topoisomerase 2-alpha)
A182V (p.Ala182Val) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
A182V (p.Ala182Val) variant details
- p.Ala182Val
- Ensembl rs868251333
- Missense
- Variant Prioritization Score for Impact Estimate 0.372
- REVEL 0.11
- CADD 24.30
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Structural context available