A182S (p.Ala182Ser) variant of TOP2A (DNA topoisomerase 2-alpha)
A182S (p.Ala182Ser) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
A182S (p.Ala182Ser) variant details
- p.Ala182Ser
- Ensembl rs867039956
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.10
- CADD 19.70
- PolyPhen-2 0.05
- SIFT 0.27
- Population evidence available
- Structural context available