A167D (p.Ala167Asp) variant of TOP2A (DNA topoisomerase 2-alpha)
A167D (p.Ala167Asp) in TOP2A (DNA topoisomerase 2-alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.76 / 1. The record also includes population frequency data and structural context.
A167D (p.Ala167Asp) variant details
- p.Ala167Asp
- Ensembl rs2143686929
- Missense
- Variant Prioritization Score for Impact Estimate 0.763
- REVEL 0.74
- CADD 27.20
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available