S57S (p.Ser57Ser) variant of TOP1 (DNA topoisomerase 1)
S57S (p.Ser57Ser) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data, published literature, and structural context.
S57S (p.Ser57Ser) variant details
- p.Ser57Ser
- rs766516532
- gnomAD 20-41076186-T-G
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.391
- CADD 13.40
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- Literature evidence available