S50S (p.Ser50Ser) variant of TOP1 (DNA topoisomerase 1)
S50S (p.Ser50Ser) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
S50S (p.Ser50Ser) variant details
- p.Ser50Ser
- rs748506884
- gnomAD 20-41061485-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.414
- CADD 12.70
- Population evidence available
- Structural context available
- Literature evidence available