S2S (p.Ser2Ser) variant of TOP1 (DNA topoisomerase 1)
S2S (p.Ser2Ser) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S2S (p.Ser2Ser) variant details
- p.Ser2Ser
- gnomAD 20-41029073-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.204
- CADD 13.40
- Population evidence available
- Structural context available
- Literature evidence available