R44R (p.Arg44Arg) variant of TOP1 (DNA topoisomerase 1)
R44R (p.Arg44Arg) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data, published literature, and structural context.
R44R (p.Arg44Arg) variant details
- p.Arg44Arg
- gnomAD 20-41061465-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.564
- CADD 13.10
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available