R31* (p.Arg31Ter) variant of TOP1 (DNA topoisomerase 1)
R31* (p.Arg31Ter) in TOP1 (DNA topoisomerase 1) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The record also includes structural context.
R31* (p.Arg31Ter) variant details
- p.Arg31Ter
- NCI-TCGA Cosmic COSV1007
- NCI-TCGA Cosmic COSV6369
- Ensembl rs2145926983
- Variant assessed as somatic; high impact.
- Stop Gained
- UniProt: Variant assessed as somatic; high impact.
- Structural context available