Q11R (p.Gln11Arg) variant of TOP1 (DNA topoisomerase 1)
Q11R (p.Gln11Arg) in TOP1 (DNA topoisomerase 1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
Q11R (p.Gln11Arg) variant details
- p.Gln11Arg
- gnomAD 20-41029095-TC-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.545
- CADD 28.70
- Population evidence available
- Structural context available
- Literature evidence available