N8N (p.Asn8Asn) variant of TOP1 (DNA topoisomerase 1)
N8N (p.Asn8Asn) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
N8N (p.Asn8Asn) variant details
- p.Asn8Asn
- gnomAD 20-41029091-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.306
- CADD 13.70
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available
- Literature evidence available