L6L (p.Leu6Leu) variant of TOP1 (DNA topoisomerase 1)
L6L (p.Leu6Leu) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L6L (p.Leu6Leu) variant details
- p.Leu6Leu
- gnomAD 20-41029085-C-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.239
- CADD 10.20
- Population evidence available
- Structural context available
- Literature evidence available