L18L (p.Leu18Leu) variant of TOP1 (DNA topoisomerase 1)
L18L (p.Leu18Leu) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
L18L (p.Leu18Leu) variant details
- p.Leu18Leu
- rs1202822680
- gnomAD 20-41029449-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.161
- CADD 11.40
- Population evidence available
- Structural context available
- Literature evidence available