K48K (p.Lys48Lys) variant of TOP1 (DNA topoisomerase 1)
K48K (p.Lys48Lys) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
K48K (p.Lys48Lys) variant details
- p.Lys48Lys
- rs35905808
- gnomAD 20-41061479-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.205
- CADD 8.14
- Population evidence available
- Structural context available
- Literature evidence available