K46K (p.Lys46Lys) variant of TOP1 (DNA topoisomerase 1)
K46K (p.Lys46Lys) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
K46K (p.Lys46Lys) variant details
- p.Lys46Lys
- rs2145927024
- gnomAD 20-41061473-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.226
- CADD 8.62
- Population evidence available
- Structural context available
- Literature evidence available