F16F (p.Phe16Phe) variant of TOP1 (DNA topoisomerase 1)
F16F (p.Phe16Phe) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
F16F (p.Phe16Phe) variant details
- p.Phe16Phe
- gnomAD 20-41029445-C-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.494
- CADD 14.40
- Population evidence available
- Structural context available
- Literature evidence available