D9D (p.Asp9Asp) variant of TOP1 (DNA topoisomerase 1)
D9D (p.Asp9Asp) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
D9D (p.Asp9Asp) variant details
- p.Asp9Asp
- gnomAD 20-41029094-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.198
- CADD 12.10
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available
- Literature evidence available