D15D (p.Asp15Asp) variant of TOP1 (DNA topoisomerase 1)
D15D (p.Asp15Asp) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
D15D (p.Asp15Asp) variant details
- p.Asp15Asp
- rs145138122
- gnomAD 20-41029442-T-C
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.451
- CADD 15.60
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available
- Literature evidence available