A14A (p.Ala14Ala) variant of TOP1 (DNA topoisomerase 1)
A14A (p.Ala14Ala) in TOP1 (DNA topoisomerase 1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
A14A (p.Ala14Ala) variant details
- p.Ala14Ala
- gnomAD 20-41029439-G-T
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.462
- CADD 15.80
- Population evidence available
- Structural context available
- Literature evidence available