T141A (p.Thr141Ala) variant of TNXB (Tenascin-X)
T141A (p.Thr141Ala) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
T141A (p.Thr141Ala) variant details
- p.Thr141Ala
- TOPMed rs1780477817
- gnomAD rs1780477817
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.07
- ESM-1b 0.00
- AlphaMissense 0.11
- CADD 23.30
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available