T122P (p.Thr122Pro) variant of TNXB (Tenascin-X)
T122P (p.Thr122Pro) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T122P (p.Thr122Pro) variant details
- p.Thr122Pro
- TOPMed rs1411732850
- gnomAD rs1411732850
- Missense
- Variant Prioritization Score for Impact Estimate 0.317
- REVEL 0.31
- ESM-1b 1.00
- AlphaMissense 0.09
- CADD 13.30
- PolyPhen-2 0.81
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available