P88S (p.Pro88Ser) variant of TNXB (Tenascin-X)
P88S (p.Pro88Ser) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
P88S (p.Pro88Ser) variant details
- p.Pro88Ser
- gnomAD rs1448988045
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.18
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 21.20
- PolyPhen-2 1.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available