P41S (p.Pro41Ser) variant of TNXB (Tenascin-X)
P41S (p.Pro41Ser) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P41S (p.Pro41Ser) variant details
- p.Pro41Ser
- cosmic curated COSV64492
- gnomAD rs1780515011
- Missense
- Variant Prioritization Score for Impact Estimate 0.392
- REVEL 0.28
- ESM-1b 0.00
- AlphaMissense 0.12
- CADD 25.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available