P41H (p.Pro41His) variant of TNXB (Tenascin-X)
P41H (p.Pro41His) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
P41H (p.Pro41His) variant details
- p.Pro41His
- cosmic curated COSV64489
- Missense
- Variant Prioritization Score for Impact Estimate 0.438
- REVEL 0.29
- ESM-1b 0.00
- AlphaMissense 0.20
- CADD 25.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available