P25R (p.Pro25Arg) variant of TNXB (Tenascin-X)
P25R (p.Pro25Arg) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
P25R (p.Pro25Arg) variant details
- p.Pro25Arg
- gnomAD rs1727980854
- Missense
- Variant Prioritization Score for Impact Estimate 0.496
- REVEL 0.41
- ESM-1b 0.00
- AlphaMissense 0.21
- CADD 25.50
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available