P25A (p.Pro25Ala) variant of TNXB (Tenascin-X)
P25A (p.Pro25Ala) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
P25A (p.Pro25Ala) variant details
- p.Pro25Ala
- gnomAD rs1475344186
- Missense
- Variant Prioritization Score for Impact Estimate 0.42
- REVEL 0.27
- ESM-1b 0.00
- AlphaMissense 0.15
- CADD 24.20
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available