K69N (p.Lys69Asn) variant of TNXB (Tenascin-X)
K69N (p.Lys69Asn) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K69N (p.Lys69Asn) variant details
- p.Lys69Asn
- ExAC rs766241196
- gnomAD rs766241196
- Missense
- Variant Prioritization Score for Impact Estimate 0.337
- REVEL 0.25
- ESM-1b 0.00
- AlphaMissense 0.87
- CADD 23.40
- PolyPhen-2 0.99
- SIFT 0.08
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available