C87Y (p.Cys87Tyr) variant of TNXB (Tenascin-X)
C87Y (p.Cys87Tyr) in TNXB (Tenascin-X) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
C87Y (p.Cys87Tyr) variant details
- p.Cys87Tyr
- TOPMed rs971564159
- Missense
- Variant Prioritization Score for Impact Estimate 0.823
- REVEL 0.80
- ESM-1b 1.00
- AlphaMissense 0.92
- CADD 26.80
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available